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Drug delivery and thrombus clearance are achieved using soft substances. Soft material reconfigurable micro robot is a kind of use of soft materials (such as gel, liquid crystal, elastomer, dielectric elastomer, etc.) manufacture of micro and nano motor, with deformable, reconfigurable and adaptive characteristics, can move in the blood vessels, and through the surface modification drugs or other functional molecules to achieve the precise treatment of lesions. Soft matter remodelable microrobot based on liquid crystal elastomer enables clearance of thrombus by surface modification of plasminogen activator. Cell manipulation and tissue engineering using soft matter reconfigurable micro-robots. Soft matter reconfigurable microrobots can adapt to different cell manipulation tasks by changing their shape, size, and function, such as cell capture, transport, separation, release, and more, and can modify and induce cells by surface modifying cells or biomolecules. A reconfigurable microrobot based on magnetic soft matter to construct myocardial tissue by surface modifying stem cells.