国产人妖在线视频I午夜av一区二区三区I国产色一区二区I一级片视频在线观看I一级毛片儿I亚色图I丁香花一区二区I超碰97在线免费I久久精品中文字幕I日韩在线视频观看免费I无码中文字幕色专区I欧美专区亚洲专区I国产tv在线观看I2024最新黄色网址I日本老妇高潮乱hdI成人免费入口I日韩精品视频在线看I国产传媒在线播放I一本岛视频在线观看I自拍日韩亚洲一区在线I国产成人亚洲综合a∨婷婷I国产精品2019I色亚洲天堂Iav黄色免费I欧美大尺度视频

Antigenic self-nano vaccine

Antigen self-nano vaccine is a vaccine that uses nanotechnology to wrap antigen in nanoparticles, thus improving the stability, immunogenicity and targeting of antigen. The vaccine can be used to prevent or treat a variety of infectious diseases and tumors.

Case of antigen-nanonanovaccine:

Tumor nano vaccine: a smart tumor nano-vaccine (TNV), the nano vaccine can drainage to the lymph nodes and effective accumulation, by antigen presentation cells intake, in response to the acidic environment in the endosomal and cathepsin, release free Toll receptor agonist, to activate the Toll on the endosomal membrane receptor 7 / 8, induce strong anti-tumor immune response, and reduce the effect of drug systemic distribution of side effects.

MRNA vaccine: An mRNA vaccine is a vaccine that uses synthetic mRNA molecules to guide cells to generate antigens that stimulate the immune response. The mRNA molecules need to enter the cells through special delivery carriers, such as lipid nanoparticles (LNP), polymer nanoparticles, etc. At present, mRNA technology has been a great success in the development of the new coronavirus vaccine, such as the new coronavirus mRNA vaccine developed by Pfizer / BioNTech and Moderna has been authorized by several regulatory agencies. Moreover, mRNA technology has also been used to develop vaccines for other infectious diseases and tumors.

Reference Documentation:

[1]Xia Heming, Qin Mengmeng, Wang Yigong. A pH-/enzyme-responsive nanoparticle selectively targets endosomal Toll-like receptors to potentiate robust cancer vaccination. Nano Letters, 2022, 22(3): 1800-1810.

[2]Pardi N, Hogan MJ, Porter FW, Weissman D. mRNA vaccines — a new era in vaccinology. Nature Reviews Drug Discovery, 2018, 17(4): 261-279.