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PTX-ILips

PTX-ILips

【Numbering】BKMC101001 【CAS】CAS
【Item No.】BKMC101001-2 【specification】
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Name: PTX-ILips
Composition: DOPE-pep-SMCC, aCD 47, PTX, and PEG2000
Size: 100-200nm
Application: Chemotherapy-immune combined with anti-tumor
Storage conditions: -4℃
Other instructions: shelf life of half a year in sealed state [main advantages] 1. Integrated combined treatment of "two birds with one stone" (PTX-ILips), Can simultaneously release both aCD 47 and paclitaxel (PTX) liposomes in response to matrix metalloproteinase 2 (MMP 2) in the TNBC tumor microenvironment, To achieve the synergistic anti-tumor effect of immune-chemotherapy; 2, aCD 47 by polarizing TAMs into M1 type macrophages by promoting TAMs in TNBC, Phagocytosis of the tumor cells, And activate the immune response of CD4 + and CD8 + T cells; 3, PTX liposomes to effectively kill tumor cells, Play an immune-chemotherapy combined with anti-tumor effect.
Title:Detachable Liposomes Combined Immunochemotherapy for Enhanced Triple-Negative Breast Cancer Treatment through Reprogramming of Tumor-Associated Macrophages
Article link:https://www.x-mol.com/news/688117



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