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Nanozyme:RuO2 NPs

Nanozyme:RuO2 NPs

【Numbering】BKMA104014 【CAS】CAS
【Item No.】BKMA104014-2 【specification】
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Name: RuO2 NPs
Composition: the RuO2
Particle size: 5 nm
Application: Acute kidney injury
Storage conditions: -4℃
Other instructions: shelf life of half a year under sealed state [main advantages] 1, NP shows excellent antioxidant activity and low biotoxicity. Alternatively, they can be excreted through the glomeruli. The combination of these features makes supersmall RuO2NP promising to be a nanoenzyme to prevent AKI. The catalytic properties of NP mimic the activities of catalase, peroxidase, superoxide dismutase, and glutathione peroxidase; 2. They can be efficiently and rapidly absorbed by human embryonic kidney cells, while significantly reducing ROS-induced apoptosis by eliminating excess ROS. Ultra-small RuO2NPs clearly inhibited the development of AKI in mice after i. v. In vivo toxicity experiments demonstrated the biosafety of NP after long-term prophylaxis.

Title:An Ultrasmall RuO2 Nanozyme Exhibiting Multienzyme-like Activity for the Prevention of Acute Kidney Injury

Article link:https://mp.weixin.qq.com/s?src=11×tamp=1688719314&ver=4635&signature=*3THxgsk-yV8yuNRV65R44SenoRyu9wnHRh-mFzM6rQV0zObiVLge-48kWTadBm*D-wlCe-c4dERR49KxAJM3afG9BjwASw2fdfpgi1no2zoKQQh79AS1e9-eMpIqls3&new=1

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    谷胱甘肽過氧化物酶(GPx)樣酶

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